Drug Standards
Apexbio Technology LLC Boceprevir 394730-60-0 10mM (in 1mL DMSO)
Boceprevir is an oral inhibitor targeting hepatitis C virus (HCV) NS3 protease an enzyme essential for processing viral polyproteins during HCV replication The compound binds directly and reversibly to the NS3 enzyme s active site forming a covalent adduct through its ketoamide functionality Cell-based replicon assays demonstrated that boceprevir inhibits HCV replication in cultured hepatocytes with an IC90 of approximately 350 nM In preclinical studies boceprevir exhibited favorable selectivity towards HCV NS3 relative to human neutrophil elastase Commonly boceprevir is used in research investigating HCV replication mechanisms and NS3 enzyme function as well as in antiviral combination assays involving interferon-based regimens
Medchemexpress LLC Carbidopa | 28860-95-9 | 99.8% | 10 MM 1 ML
Carbidopa, also known as (S)-(-)-Carbidopa, is a peripheral decarboxylase inhibitor primarily used for research related to Parkinson's disease. It also functions as a selective aryl hydrocarbon receptor (AhR) modulator and has been shown to inhibit pancreatic cancer cell and tumor growth.
- Acts as a peripheral decarboxylase inhibitor
- Functions as a selective aryl hydrocarbon receptor (AhR) modulator
- Demonstrates anticancer activity by inhibiting pancreatic cancer cell and tumor growth
- High purity of 99.84% ensures reliability for research applications
- Comprehensive documentation available, including Data Sheet, COA, SDS, HNMR, RP-HPLC, and Handling Instructions
- Detailed solubility information provided for in vitro and in vivo applications, with protocols for preparing clear stock and working solutions
- Intended for research use only
Medchemexpress LLC Naphazoline hydrochloride | 550-99-2 | 99.4% | 10 MM * 1 ML
Naphazoline hydrochloride is a potent α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It also decreases the levels of inflammatory factors (TNF-α, IL-1β, and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. This compound can be used for non-bacterial conjunctivitis research and is intended for research use only, not sold to patients.
- Potent α-adrenergic receptor agonist
- Reduces vascular hyperpermeability and promotes vasoconstriction
- Decreases inflammatory factors (TNF-α, IL-1β, and IL-6)
- Decreases cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF
- Suitable for non-bacterial conjunctivitis research
Medchemexpress LLC Diltiazem | 42399-41-7 | 99.7% | 500 MG
Diltiazem is an orally active L-type Ca2+ channel blocker. It exhibits antihypertensive and antiarrhythmic effects and is utilized in research for cardiac arrhythmia, hypertension, and angina pectoris.
- Acts as an L-type calcium channel blocker
- Shows antihypertensive and antiarrhythmic effects
- Useful for cardiac arrhythmia research
- Applicable for hypertension and angina pectoris research
- Demonstrated antiproliferative activity in certain cell lines
- Inhibits P-glycoprotein-mediated multidrug resistance
- Prevents aortic aneurysm formation in animal models
Medchemexpress LLC Glipizide (Standard) | 29094-61-9 | 99.7% | 100 MG
Glipizide (Standard) is an analytical standard intended for research and analytical applications. This potent, orally active sulfonylurea class anti-diabetic agent is used for type 2 diabetes mellitus research, acting by partially blocking ATP-sensitive potassium channels among β cells of pancreatic islets of Langerhans.
- Analytical standard for research and analytical applications
- Potent, orally active sulfonylurea class anti-diabetic agent
- Used for type 2 diabetes mellitus research
- Acts by partially blocking ATP-sensitive potassium (KATP) channels
- Reference standard supplied assay
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS
Apexbio Technology LLC Tenofovir 147127-20-6 10mM (in 1mL DMSO)
Tenofovir is an antiviral compound acting as an inhibitor of HIV reverse transcriptase specifically targeting RNA-dependent DNA polymerase to impede the replication cycle of HIV It interferes with the transcription process by competitively binding to the enzyme thereby preventing viral RNA from being transcribed into complementary DNA In vitro investigations indicate that Tenofovir inhibits viral replication as evidenced by an IC50 value of approximately 1 5 M in SIV-infected C-8166 cell assays Due to this inhibitory mechanism and antiviral activity against HIV Tenofovir is widely employed in biomedical and pharmacological research focused on HIV infection antiviral drug development and related studies involving reverse transcriptase enzymatic activity
Medchemexpress LLC Amoxicillin | 26787-78-0 | 99.9% | 1 G
Amoxicillin is an antibiotic with good oral absorption and broad-spectrum antimicrobial activity. It functions by inhibiting the biosynthesis of polypeptides in the cell wall, which in turn inhibits cell growth. It is intended for research use only.
- Good oral absorption
- Broad-spectrum antimicrobial activity
- Inhibits biosynthesis of polypeptides in the cell wall
- Inhibits cell growth
- Intended for research use only
Apexbio Technology LLC Ivermectin 70288-86-7 10mM (in 1mL DMSO)
Ivermectin is a positive allosteric modulator of neuronal nicotinic acetylcholine receptors ( 7 nAChR) and purinergic receptors (P2X4) Additionally ivermectin influences chloride ion channels regulated by glutamate and GABA and also enhances glycine receptor-mediated currents at low concentrations It is commonly employed in neuropharmacological research examining receptor function ion channel activity and neurotransmitter signaling pathways As an anthelmintic ivermectin is widely used in parasitology research for its inhibition of parasite neuromuscular transmission Reported IC50 values vary among receptor types generally ranging from nanomolar to micromolar levels depending on assay conditions and biological context
Medchemexpress LLC Ciclopirox olamine | 41621-49-2 | 99.8% | 1 ML
Ciclopirox olamine is a synthetic and orally active antifungal agent used for superficial mycoses research. It has a very broad spectrum of activity, inhibiting dermatophytes, yeasts, molds, and many pathogenic Gram-positive and Gram-negative species. Additionally, Ciclopirox olamine exhibits anticancer and anti-inflammatory effects.
- Synthetic and orally active antifungal agent
- Broad spectrum of activity against dermatophytes, yeasts, molds, and many pathogenic Gram-positive and Gram-negative species
- Exhibits anticancer effects
- Exhibits anti-inflammatory effects
Medchemexpress LLC Fenoldopam (mesylate) | 67227-57-0 | 99.9% | 50 MG
Fenoldopam (mesylate) | 67227-57-0 | 99.9% | 50 MG
Medchemexpress LLC Isosorbide dinitrate | 87-33-2 | 99.9% | 1 ML
Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI). It is for research use only.
- Prevents LV remodeling
- Prevents degradation of cardiac function
- Improves pulmonary artery pressure
- Exhibits cardioprotective effect against myocardial ischemia-reperfusion injury
- Solid appearance
- White to off-white color
- High purity
Medchemexpress LLC Tebipenem pivoxil | 161715-24-8 | MFCD17215369 | 99.7% | 1 ML
Tebipenem pivoxil is an orally active antibiotic effective against various pathogenic bacteria. It functions by binding to penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis.
- Orally active antibiotic
- Effective against various pathogenic bacteria
- Inhibits cell wall synthesis
- High purity of 99.7%
Medchemexpress LLC Ciprofloxacin-d8 hydrochloride | 1216659-54-9 | 98.8% | 1 MG
Ciprofloxacin-d8 hydrochloride is the deuterium labeled Ciprofloxacin. This fluoroquinolone antibiotic exhibits potent antibacterial activity.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS